FERMITINS, THE ORTHOLOGS OF MAMMALIAN KINDLINS, REGULATE THE DEVELOPMENT OF A FUNCTIONAL CARDIAC SYNCYTIUM IN DROSOPHILA MELANOGASTER.

Fermitins, the orthologs of mammalian Kindlins, regulate the development of a functional cardiac syncytium in Drosophila melanogaster.

The vertebrate Kindlins are an evolutionarily conserved family of proteins critical for integrin signalling and cell adhesion.Kindlin-2 (KIND2) is associated with intercalated discs in mice, suggesting a role in cardiac syncytium development; however, deficiency of Kind2 leads to embryonic lethality.Morpholino knock-down of Kind2 in zebrafish has a

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Collecting Coins and Medals in 18th-Century Sweden

During the 18th century, collections of coins and medals were familiar sights.The collectors ranged from scholars to amateurs, men and women and the collectables Gift Card tempted collectors for various reasons: they signified wealth and knowledge, they rendered historical events or current politics in material form, or they were miniature artworks

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Phenylboronic acid conjugated multifunctional nanogels with 131I-labeling for targeted SPECT imaging and radiotherapy of breast adenocarcinoma

We report a new 131I-labeling functional platform for targeted single-photon emission computed tomography (SPECT) imaging and radiotherapy of breast adenocarcinoma.In this study, polyethyleneimine (PEI) based Activity Equipment nanogels (P.NH2 NGs) were prepared by water/oil polymerization, modified with targeted agent phenylboronic acid (PBA), and

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